Increasing global incidence of central precocious puberty

Precocious puberty is a prevalent endocrine disorder that affects children globally. Classically, precocious puberty is defined as the development of secondary sexual characteristics before age 8 years in girls and 9 years in boys and it has a clear female predominance.

Noonan syndrome

Noonan syndrome is a relatively common autosomal dominant disorder characterised by facial dysmorphism, short stature, chest deformities and congenital heart defects.

The genetic toolbox: dissecting pathways to growth

The role of growth hormone has been established for many decades, but it is only with the advent of advanced molecular genetic techniques that researchers have started to piece together the precise pathways leading to growth.