Puberty disorders

Gonadotropin-releasing hormone analogue therapy offers a similar benefit to girls with early fast puberty as it does to those with central precocious puberty, the results of an observational study suggest.

Gonadotropin-releasing hormone agonist therapy in children with congenital adrenal hyperplasia does not compromise bone mineral density, US researchers say.

Applying a machine learning technique to hormone measurements can help determine whether a girl with early signs of puberty has nonprogressive premature thelarche or may require treatment for idiopathic central precocious puberty, suggest study findings published in The Journal of Clinical Endocrinology & Metabolism.

Adolescents with a history of idiopathic central precocious puberty may be at increased risk of polycystic ovary syndrome, researchers report.