Supporting families of paediatric patients with adrenal disease
While adrenal disease in children is quite rare, healthcare professionals today working in paediatric endocrinology departments are experts in managing the care of children with adrenal disease.
Medical management of congenital adrenal hyperplasia: can conventional therapy be replaced by novel treatments?
Congenital adrenal hyperplasia is a disorder of decreased cortisol production coupled with an increase in androgens from a compensatory adrenocorticotropic hormone drive.
Increasing global incidence of central precocious puberty
Precocious puberty is a prevalent endocrine disorder that affects children globally. Classically, precocious puberty is defined as the development of secondary sexual characteristics before age 8 years in girls and 9 years in boys and it has a clear female predominance.
Noonan syndrome
Noonan syndrome is a relatively common autosomal dominant disorder characterised by facial dysmorphism, short stature, chest deformities and congenital heart defects.
The genetic toolbox: dissecting pathways to growth
The role of growth hormone has been established for many decades, but it is only with the advent of advanced molecular genetic techniques that researchers have started to piece together the precise pathways leading to growth.
Common genetic variants of pubertal timing
Delayed puberty is common in the developed world, affecting over 2% of adolescents, and is associated with adverse health outcomes including short stature, reduced bone mineral density and compromised psychosocial health.
Congenital adrenal hyperplasia: optimising cardiometabolic outcomes
The introduction of glucocorticoid replacement for congenital adrenal hyperplasia has revolutionised the outlook for patients with this lifelong condition, preventing life-threatening salt-wasting crises.
