Type 1/monogenic diabetes
NEWS
The European Society for Paediatric Endocrinology (ESPE) has released a position statement to encourage further research into endocrine immune-related adverse events associated with the use of immune checkpoint inhibitors in children with cancer.
Researchers have characterised the pathogenesis, prognosis, treatment, neurological sequelae and prevalence of congenital hyperinsulinism in children born in Norway, finding genetic alterations to ABCC8 to be the most common cause of the condition.
A study of children from Qatar with severe early-onset obesity suggests that around 15% of cases may be explained by rare genetic variants within the leptin–melanocortin pathway and other signalling pathways.
Neurodevelopmental disorders are frequent and diverse in children with hyperinsulinism/hyperammonaemia syndrome caused by a GLUD1 mutation, a study shows.
In depth
Programme Director Professor Martin Savage is joined by experts to present and discuss the application of precision medicine in endocrine disorders, offering clinical expertise and insight, evidence and opinion on this topic.
