Pituitary/growth disorders


A study of preterm boys shows increased androgen levels at the estimated time of birth in those with low birthweight.
Using both height and deviation from height target during growth monitoring could improve detection of pathological growth disorders in children and avoid unnecessary clinic referrals, suggest UK researchers who found the current criteria to have low sensitivity.
Childhood-onset combined pituitary hormone deficiency occurs in around one in 16,000 children, but its diagnosis is often delayed due to nonspecific presenting symptoms, say researchers.
A systematic review and meta-analysis confirms a high rate of reversal of idiopathic growth hormone deficiency, albeit strongly dependent on the peak GH cutoff used.

In depth

A 4-year-old girl is referred to the local paediatric endocrine unit with signs of pubertal development.
The evaluation of children presenting with short stature includes detailed clinical, phenotypic, auxological and biochemical assessments with genetic analyses in selected cases.
Programme Director Professor Martin Savage is joined by experts to present and discuss the application of precision medicine in endocrine disorders, offering clinical expertise and insight, evidence and opinion on this topic.
A 14-year-old boy is referred by his doctor with concerns about his growth.
Martin Savage
Programme Director

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