Thyroid disorders


The majority of sporadic medullary thyroid cancer cases in children may be positive for RET mutations that are potentially amenable to treatment with a targeted agent, suggests research published in the Journal of Clinical Endocrinology & Metabolism.
Over a third of children diagnosed with congenital hypothyroidism have discontinued treatment within 10 years of diagnosis, say French researchers who have identified predictive markers for a transient prognosis.
Children using an oral solution of levo-thyroxine for treatment of congenital hypothyroidism may require closer monitoring during the first few months than those using tablet formulations, say researchers.
Researchers find that teenagers with endocrine disorders often have gaps in their knowledge of their condition and how to manage it, making them poorly prepared for transition to adult clinic.

In depth

Read the discussion on the genetics and clinical consequences of dominant-negative growth hormone receptor alterations.
Congenital hypothyroidism guidelines: has anything changed?
Programme Director Professor Martin Savage is joined by experts to present and discuss the application of precision medicine in endocrine disorders, offering clinical expertise and insight, evidence and opinion on this topic.
Our podcast features Dr Salvatore Vaccarella, from the International Agency for Research on Cancer in Lyon, France, lead author of a recent article in The Lancet Diabetes & Endocrinology indicating that thyroid cancer overdiagnosis is a concern for children and adolescents.
Martin Savage
Programme Director
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