Join Professor Martin Savage and expert colleagues for this series of interviews as they explore different perspectives and insights into how to successfully implement precision medicine into the management of paediatric endocrine disorders.
A 4-year-old boy of Bangladeshi origin was referred to paediatric endocrine clinic by his community paediatrician due to concerns of precocious puberty.
WEBCAST NOW AVAILABLE This is the 9th IMAGE programme, which focuses on transgender management, bone health, and the genetics and treatment of growth disorders.
Professor Martin Savage discusses the roles of clinical, endocrinological and genetic testing in the diagnosis and care of children with idiopathic short stature.
Genetic variations in genes regulating the growth plate appear to play a “central role” in the aetiology of persistent short stature among children born small for gestational age, report researchers from the Czech Republic.
Researchers have identified two naturally occurring, dominant-negative variants in the growth hormone receptor gene that act via the same molecular mechanism and contribute to the nonclassical growth hormone insensitivity phenotype.
Observational data confirm that children born small for gestational age achieve the best growth outcomes if they start treatment with recombinant human growth hormone as young as possible.