Adrenal disorders

Preliminary trial findings published in the Journal of Clinical Endocrinology & Metabolism point to the possible use of a glucagon analogue for the treatment of congenital hyperinsulinism in children.

Adrenal insufficiency is a common clinical feature in children and young adults with single large-scale mitochondrial DNA deletions, especially in those with Pearson syndrome, Italian researchers have found.

Children and adolescents with ectopic adrenocorticotropic hormone syndrome show a different aetiological profile to that of adults, suggests a systematic review of the literature.

A diagnosis of pseudohypoparathyroidism type IA should be considered for infants who present with a combination of congenital hypothyroidism, parathyroid hormone resistance, early-onset obesity or minor dysmorphic features, Israeli clinicians suggest.