Immune checkpoint inhibitors: Transforming cancer care, challenging endocrine health
Find out about the risks and management of endocrine adverse events in children and adolescents undergoing immune checkpoint therapy for cancer.
Guidance for the clinician: achondroplasia management in 2025
Read our expert review on the management of growth and complications for children with achondroplasia.
Management of small for gestational age patients
In our latest expert review, Rosario Ferrigno discusses children born small for gestational age are defined as those having birth weight and/or length below –2 standard deviation score for gestational age.
The broad phenotypic spectrum of growth hormone insensitivity disorders
In our latest expert review, Afiya Andrews outlines the broad phenotypic spectrum of classical and non-classical growth hormone insensitivity disorders in children.
Therapeutic advances in congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Find out more about this group of rare autosomal recessive conditions affecting the adrenal cortex called Congenital adrenal hyperplasia (CAH).
Rare genetic causes of primary adrenal insufficiency excluding congenital adrenal hyperplasia
Find out more about the rare genetic causes of paediatric adrenal insufficiency and how best to treat affected children.
Dominant-negative growth hormone receptor mutations: Genetics and clinical consequences
Read the discussion on the genetics and clinical consequences of dominant-negative growth hormone receptor alterations.
Congenital hypothyroidism guidelines: has anything changed?
Congenital hypothyroidism guidelines: has anything changed?
Why is the growth plate the most important organ for childhood growth: how can it be investigated for clinical diagnosis?
Why is the growth plate the most important organ for childhood growth: how can it be investigated for clinical diagnosis?
Personalised medicine for hypophosphataemic rickets – a new era
Rickets results from impaired mineralisation of the growth plate. Hypophosphataemia is common to all forms of rickets as hypophosphataemia impairs both hydroxyapatite formation and failure of apoptosis of the hypertrophied chondrocytes.
