Over a third of children diagnosed with congenital hypothyroidism have discontinued treatment within 10 years of diagnosis, say French researchers who have identified predictive markers for a transient prognosis.
Children using an oral solution of levo-thyroxine for treatment of congenital hypothyroidism may require closer monitoring during the first few months than those using tablet formulations, say researchers.
Programme Director Professor Martin Savage is joined by experts to present and discuss the application of precision medicine in endocrine disorders, offering clinical expertise and insight, evidence and opinion on this topic.
Researchers find that teenagers with endocrine disorders often have gaps in their knowledge of their condition and how to manage it, making them poorly prepared for transition to adult clinic.
Our podcast features Dr Salvatore Vaccarella, from the International Agency for Research on Cancer in Lyon, France, lead author of a recent article in The Lancet Diabetes & Endocrinology indicating that thyroid cancer overdiagnosis is a concern for children and adolescents.
Researchers have detected a global increase in the incidence of thyroid cancer among children and adolescents similar to that reported for the adult population, raising concerns that screening-related overdiagnosis may also be occurring in young people.
A longitudinal study of Finnish patients with juvenile acquired hypothyroidism has revealed that an abnormal growth pattern may be present for up to 5 years before diagnosis.
Effective detection of newborn babies with congenital hypothyroidism requires a repeat screen with a lower thyroid-stimulating hormone cutoff for at-risk infants, research suggests.
A randomised trial of children receiving treatment for thyrotoxicosis shows no difference in biochemical stability between block-and-replace and dose-titration strategies.
Primary ovarian insufficiency affects the majority of girls with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, in most cases occurring before they have attained their final adult height, show data from a national cohort.
