Earlier age at diagnosis of childhood differentiated thyroid cancer is associated with a greater risk of advanced disease, but overall, patients have excellent long-term survival irrespective of age, stage, and treatment response, US study findings indicate.
The European Society for Paediatric Endocrinology (ESPE) has released a position statement to encourage further research into endocrine immune-related adverse events associated with the use of immune checkpoint inhibitors in children with cancer.
Radioactive iodine therapy may be avoided for some children undergoing surgery for papillary thyroid carcinoma, suggest findings from a study that shows good outcomes even for those with cervical lymph node metastases.
Central congenital hypothyroidism is frequently missed in Israeli infants despite a newborn screening programme for thyroid dysfunction, shows research published in the Journal of Clinical Endocrinology & Metabolism.
The majority of sporadic medullary thyroid cancer cases in children may be positive for RET mutations that are potentially amenable to treatment with a targeted agent, suggests research published in the Journal of Clinical Endocrinology & Metabolism.
Read the discussion on the genetics and clinical consequences of dominant-negative growth hormone receptor alterations.
Congenital hypothyroidism guidelines: has anything changed?
Over a third of children diagnosed with congenital hypothyroidism have discontinued treatment within 10 years of diagnosis, say French researchers who have identified predictive markers for a transient prognosis.
Children using an oral solution of levo-thyroxine for treatment of congenital hypothyroidism may require closer monitoring during the first few months than those using tablet formulations, say researchers.
Programme Director Professor Martin Savage is joined by experts to present and discuss the application of precision medicine in endocrine disorders, offering clinical expertise and insight, evidence and opinion on this topic.
