Effective detection of newborn babies with congenital hypothyroidism requires a repeat screen with a lower thyroid-stimulating hormone cutoff for at-risk infants, research suggests.
A randomised trial of children receiving treatment for thyrotoxicosis shows no difference in biochemical stability between block-and-replace and dose-titration strategies.
Primary ovarian insufficiency affects the majority of girls with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, in most cases occurring before they have attained their final adult height, show data from a national cohort.
An extensive multinational study of patients with disordered thyroid hormone transport due to MCT8 deficiency has identified key characteristics that could help early diagnosis and the treatment of underlying risk factors associated with a poor outcome in affected patients.
Factors including age at diagnosis and the specific disease influence the likelihood of children with chronic endocrine conditions being lost to follow-up, show French study findings.
Our podcast with Dr Sogol Mostoufi, from the Children’s Hospital of Philadelphia in Pennsylvania, USA, focuses on the treatment-related endocrine side effects commonly experienced by childhood cancer survivors, and the need for screening, life-long follow-up and treatment in this high-risk population.
Cases of neonatal severe hyperparathyroidism fall into two distinct categories determined by the number of causative genetic variants, which can be distinguished simply by measuring maximal calcium levels, say researchers.
A 4-year-old girl, referred to the Paediatric Assessment Unit by the GP, with a 2-week history of a cough, feeling unwell, and tired. Accompanied by her mother.
A once-daily regimen of the thyroid hormone analogue Triac normalised serum levels of tri-iodothyronine in a phase II trial of paediatric and adult patients with transporter monocarboxylate transporter 8 deficiency.
In our first edition, Professor Frederic Castinetti discussing the results of an international collaboration to study the natural history and treatment outcomes of multiple endocrine neoplasia type 2B, and Professor Martin Savage comments on a randomized trial of letrozole versus testosterone in boys with constitutional delay of growth and puberty.
