Researchers report that good outcomes are possible for children with autosomal recessive pseudohypoaldosteronism type 1, despite its high morbidity and mortality risk.
Italian researchers report presenting characteristics and outcomes for children with primary adrenal insufficiency not caused by 21-hydroxylase deficiency congenital adrenal hyperplasia.
The diagnosis of central congenital hypothyroidism with or without multiple pituitary hormone deficiencies is frequently missed in children, even among those admitted to hospital, say Dutch researchers.
While adrenal disease in children is quite rare, healthcare professionals today working in paediatric endocrinology departments are experts in managing the care of children with adrenal disease.
Hydrocortisone granules provide a straightforward and accurate means of treating infants and young children with congenital adrenal hyperplasia, with the largest issue being weaning them off sweetened pharmacy-compounded powder, research shows.
Primary ovarian insufficiency affects the majority of girls with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, in most cases occurring before they have attained their final adult height, show data from a national cohort.
Congenital adrenal hyperplasia is a disorder of decreased cortisol production coupled with an increase in androgens from a compensatory adrenocorticotropic hormone drive.
Three-week-old baby referred to the paediatric endocrine clinic from a general paediatrician with ambiguous genitalia, accompanied by very anxious and upset parents.
Giving hydrocortisone four times daily at a time-varying dose may be the best approach for children with congenital adrenal hyperplasia, say the authors of a pharmaco-kinetic and pharmaco-dynamic modelling study.
Factors including age at diagnosis and the specific disease influence the likelihood of children with chronic endocrine conditions being lost to follow-up, show French study findings.
