50-year study of boys illustrates long-term trend towards earlier puberty
July 30, 2019
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A Swedish study suggests that, as with girls, puberty has shifted to begin at an earlier age in boys.
Topic: Puberty
Research Focus: MEN-2B treatment outcomes and letrozole for delayed puberty
April 1, 2019
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In our first edition, Professor Frederic Castinetti discussing the results of an international collaboration to study the natural history and treatment outcomes of multiple endocrine neoplasia type 2B, and Professor Martin Savage comments on a randomized trial of letrozole versus testosterone in boys with constitutional delay of growth and puberty.
Common genetic variants of pubertal timing
April 1, 2019
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Delayed puberty is common in the developed world, affecting over 2% of adolescents, and is associated with adverse health outcomes including short stature, reduced bone mineral density and compromised psychosocial health.
Letrozole shows promise for treating constitutional delay of growth and puberty in boys
January 24, 2019
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Boys with constitutional delay of growth and puberty achieve greater testicular growth during 6 months of treatment with letrozole than with low-dose testosterone, show the findings of a randomised trial.
