Growth disorder
June 30, 2021
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A 14-year-old boy is referred by his doctor with concerns about his growth.
Topic: Puberty
Bodyweight link to androgen production in prepubertal children confirmed
May 27, 2021
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Measures of obesity are significantly associated with increased androgen production in children, even in the absence of physical signs of puberty, researchers report.
Knowledge gaps make teens with endocrine disorders unready for transition to adult clinic
April 27, 2021
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Researchers find that teenagers with endocrine disorders often have gaps in their knowledge of their condition and how to manage it, making them poorly prepared for transition to adult clinic.
MRI screening ‘most efficient approach’ for CNS lesions in girls with central precocious puberty
April 27, 2021
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Routine use of magnetic resonance imaging for girls with central precocious puberty is the best way to identify occult central nervous system lesions, say Turkish researchers.
BMI link to earlier puberty onset in boys confirmed
March 1, 2021
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Longitudinal study findings support a relationship between body mass index and the timing of puberty in boys, with a link found between obesity and precocious gonadarche.
Severity of MKRN3 mutation may influence CPP phenotype
February 1, 2021
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Familial central precocious puberty caused by mutations in the makorin RING finger protein 3 gene is phenotypically similar to idiopathic forms, although it can vary with the severity of the mutation, a study shows.
Translational advances in the management of growth and puberty disorders
November 5, 2020
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Watch the webcast that was recorded in São Paolo with regional experts Dr Alexander Jorge and Professor Ana Claudia Latronico. We discussed the translational advances in Latin America and how an improved understanding of the genetics have contributed to the diagnostics and treatment of growth and puberty disorders.
Rates of CPP and normal variant puberty on the rise
November 2, 2020
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The incidences of central precocious puberty and normal variant puberty have risen over the past 20 years, in line with overall population trends for earlier puberty in both girls and boys, say researchers.
Ovarian failure common, usually during childhood, in girls with APECED
September 1, 2020
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Primary ovarian insufficiency affects the majority of girls with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, in most cases occurring before they have attained their final adult height, show data from a national cohort.
MKRN3 gene deletion can cause central precocious puberty without PWS
June 30, 2020
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Whole-gene deletion of MKRN3 can cause central precocious puberty without any features of Prader–Willi syndrome, researchers report.
