Phase 2 trial results support use of the melanocortin-4 receptor agonist setmelanotide for the treatment of rapid excess weight gain and hunger in patients with hypothalamic obesity.
Vosoritide treatment appears to increase growth velocity in children with hypochondroplasia and is well tolerated, show study findings
Patients with adamantinomatous craniopharyngioma can be grouped into two distinct clusters based on their DNA methylation profile, Brazilian researchers report.
The Insights into MAnaging Growth for Endocrine nurses (IMAGE) March 2024 Meeting, organised by Springer Healthcare IME, provides high-quality, practical clinical training for nurses involved in paediatric endocrinology practice.
The Guideline Development Group has created a set of UK guidelines to aid clinicians in the diagnosis and treatment of children and young people with adamantinomatous craniopharyngiomas.
Research shows that growth hormone stimulation testing failure is more common in children with short stature or impaired linear growth who also have a diagnosis of attention deficit hyperactivity disorder.
Measuring morning salivary cortisol can be used to assess hypothalamic–pituitary–adrenal axis recovery in children who have completed a prolonged period of corticosteroid therapy, show study findings published in Hormone Research in Paediatrics.
Childhood-onset combined pituitary hormone deficiency occurs in around one in 16,000 children, but its diagnosis is often delayed due to nonspecific presenting symptoms, say researchers.
Children with growth hormone deficiency maintain their growth trajectories if they switch from a daily recombinant human growth hormone to weekly lonapegsomatropin, and the vast majority prefer the less frequent injections, show the results of the fliGHt trial.
Treatment with recombinant human growth hormone results in an increased final adult height in children with molecularly confirmed Silver–Russell syndrome, as well as an improved BMI that persists after treatment cessation, say researchers.
