Treatment with a C-type natriuretic peptide prodrug significantly increases annualised growth velocity in children with achondroplasia and offers additional health benefits, say the APPROACH trial investigators.
US researchers have created age- and sex-adjusted growth charts for use in children with classic congenital adrenal hyperplasia, reflecting the distinct patterns of height and weight among patients versus the general population.
Italian clinicians have published a set of consensus statements on the multidisciplinary diagnosis, care and treatment of patients with Noonan syndrome from childhood and beyond.
The first 2 years of recombinant growth hormone therapy offers significant benefits for prepubertal children with Silver–Russell syndrome, French researchers have found.
Plasma and urine analyses are both reliable screening tests for the diagnosis of phaeochromocytoma/paraganglioma in children and adolescents, report researchers in Clinical Endocrinology.
An artificial intelligence-assisted tool can speed up anthropometric calculations for paediatric endocrinologists monitoring growth in children with achondroplasia, research indicates.
Genetic testing has identified a likely cause for nonfamilial tall stature in 11% of children examined, show study findings published in the European Journal of Pediatrics.
Research from the Netherlands suggests that the majority of children heterozygous for pathogenic alterations to the NPR2 gene, resulting in mild skeletal dysplasia, respond to growth hormone therapy.
The European Society for Paediatric Endocrinology (ESPE) has released a position statement to encourage further research into endocrine immune-related adverse events associated with the use of immune checkpoint inhibitors in children with cancer.
For teenage boys with idiopathic short stature (ISS), combining a third-generation aromatase inhibitor with recombinant human growth hormone therapy can significantly improve adult height, suggest study findings published in the Journal of Clinical Endocrinology & Metabolism.
