Novel ‘BDV syndrome’ has considerable clinical overlap with PWS
September 1, 2021
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Researchers describe a novel autosomal recessive genetic syndrome that may be misdiagnosed as Prader–Willi syndrome.
Topic: Obesity
Childhood obesity linked to decreased penile length in puberty
August 2, 2021
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Overweight and obese boys have reduced testosterone levels and shorter penises during puberty than their normal-weight counterparts, study findings demonstrate in The Journal of Clinical Endocrinology & Metabolism.
Cardiological tests indicated in melanocortin pathway mutations linked to reduced cardiac mass
July 5, 2021
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Children with monogenic obesity linked to mutations in the leptin-melanocortin pathway have lower cardiac muscle mass than other obese children, as well as greater tissue storage of sodium, research suggests.
Prader-Willi syndrome – Holistic care for a new PWS diagnosis
February 1, 2021
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A 6 years and 5-month-old girl with Prader-Willi Syndrome attends endocrine clinic with her mother.
Setmelanotide shows efficacy at phase 3 for POMC and LEPR deficiency obesity
December 1, 2020
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The melanocortin 4 receptor agonist setmelanotide has significantly reduced hunger and resulted in weight loss in a phase 3 trial involving patients, including children, with pro-opiomelanocortin or leptin receptor deficiency obesity.
Prader-Willi Syndrome – growth hormone and beyond
September 30, 2020
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Dr Cheri Deal discusses the use of growth hormone in children with Prader-Willi syndrome, the importance of multidisciplinary care and the future of treatment for this genetic condition.
Early childhood obesity predicts preteen cardiometabolic risk
August 3, 2020
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Being overweight or obese in early childhood is associated with having increased cardiometabolic risk in preteens, researchers report.
Meta-analysis confirms growth hormone therapy benefits in Prader–Willi syndrome
June 2, 2020
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A meta-analysis confirms growth and body composition benefits for children with Prader–Willi syndrome given recombinant human growth hormone.
Liraglutide enhances weight loss in obese adolescents
May 4, 2020
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Adding liraglutide 3.0 mg to lifestyle therapy increases weight loss in obese adolescents, show the findings of a placebo-controlled phase 3 trial.
Glucose tolerance test may be best for type 2 diabetes diagnosis in youth
March 30, 2020
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An oral glucose tolerance test may identify youths with a more adverse cardiometabolic profile than a fasting plasma glucose test does, say researchers.
