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Topic: Growth disorders

Digital developments and precision medicine in paediatric growth disorder management

November 5, 2020 No Comments

Professor Savage was joined by growth disorder and digital health specialists to address resistant factors to the adoption of technology, and demonstrate how, despite a lack of published data on the efficacy of digital tools, supporting evidence of their effectiveness in other endocrine disorders, such as diabetes, can also be applied to paediatric growth disorder management.

Bone growth biomarker may provide growth velocity snapshot

November 2, 2020 No Comments

A single measurement of plasma levels of a fragment of type X collagen (Collagen X bioMarker) may give an instant picture of how fast a child is growing, say researchers.

Idiopathic short stature is not a diagnosis: A strategy is needed to identify the true pathogenesis in cases of unexplained short stature

November 1, 2020 No Comments

The designation “Idiopathic short stature” was first used in the 1980s as a description for short children who had normal growth hormone secretion and otherwise unexplained short stature.

Vosoritide ‘effective’ for increasing growth in children with achondroplasia

October 12, 2020 No Comments

The C-type natriuretic peptide analogue vosoritide significantly increases the growth rate of children with achondroplasia, indicate the results of a randomised, double-blind phase 3 study published in The Lancet.

Copy number variants enriched among GH-, IGF-1-insensitive patients

October 12, 2020 No Comments

Rare copy number variants have been identified in a study of children who have growth hormone insensitivity or insulin-like growth factor-1 insensitivity, shedding light on the genetic basis of their conditions

Prader-Willi Syndrome – growth hormone and beyond

September 30, 2020 No Comments

Dr Cheri Deal discusses the use of growth hormone in children with Prader-Willi syndrome, the importance of multidisciplinary care and the future of treatment for this genetic condition.

The safety profile of growth hormone

September 1, 2020 No Comments

Our podcast with consortium member, Stefano Cianfarani, from the University of Rome Tor Vergata, Italy, discusses the safety of growth hormone.

Most brain MRIs may be unnecessary in isolated GHD diagnosis

September 1, 2020 No Comments

Less than 10% of brain magnetic resonance imaging scans in children with isolated growth hormone deficiency reveal a pathological cause, say researchers.

Type and site of radiotherapy may impact future response to GH therapy in cancer survivors

September 1, 2020 No Comments

Children who receive total body irradiation or craniospinal radiation for cancer may have a reduced response to growth hormone therapy if they later require it, say researchers.

IMAGE 2020

August 26, 2020 No Comments

This was the 7th IMAGE conference which focuses on dysmorphic and genetic short stature syndromes and transitional care.

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