Exome sequencing and chromosomal microarray analysis are useful tools for the identification of genetic causes underlying short stature, indicate the results of a systematic review and meta-analysis.
Gonadotropin-releasing hormone agonist therapy in children with congenital adrenal hyperplasia does not compromise bone mineral density, US researchers say.
The Insights into MAnaging Growth for Endocrine nurses (IMAGE) March 2024 Meeting, organised by Springer Healthcare IME, provides high-quality, practical clinical training for nurses involved in paediatric endocrinology practice.
Adolescents with a history of idiopathic central precocious puberty may be at increased risk of polycystic ovary syndrome, researchers report.
Two-year findings from the REAL4 trial support a switch from daily growth hormone to a weekly dose of the long-acting derivative somapacitan for prepubertal children with GH deficiency.
Multifocal disease does not predict a poor outcome in children and adolescents with papillary thyroid cancer, suggest study findings from the Memorial Sloan Kettering Cancer Center in New York, USA.
Research shows that growth hormone stimulation testing failure is more common in children with short stature or impaired linear growth who also have a diagnosis of attention deficit hyperactivity disorder.
Women diagnosed with non-classical congenital adrenal hyperplasia during childhood or adolescence do not typically reach their target height, but this is not related to glucocorticoid treatment duration and dose, research shows.
Genetic variations in genes regulating the growth plate appear to play a “central role” in the aetiology of persistent short stature among children born small for gestational age, report researchers from the Czech Republic.
Researchers have identified two naturally occurring, dominant-negative variants in the growth hormone receptor gene that act via the same molecular mechanism and contribute to the nonclassical growth hormone insensitivity phenotype.
