CAH-specific growth charts aid clinical management during childhood
US researchers have created age- and sex-adjusted growth charts for use in children with classic congenital adrenal hyperplasia, reflecting the distinct patterns of height and weight among patients versus the general population.
Noonan syndrome consensus statements guide lifelong care
Italian clinicians have published a set of consensus statements on the multidisciplinary diagnosis, care and treatment of patients with Noonan syndrome from childhood and beyond.
Age at childhood differentiated thyroid cancer diagnosis linked to disease severity
Earlier age at diagnosis of childhood differentiated thyroid cancer is associated with a greater risk of advanced disease, but overall, patients have excellent long-term survival irrespective of age, stage, and treatment response, US study findings indicate.
Study highlights anti-fracture drug underuse in osteogenesis imperfecta
Children with osteogenesis imperfecta are more likely to use anti-fracture drugs than their older counterparts, but underuse is common across all age groups, US study findings indicate.
Early growth hormone offers height and nutritional benefits in Silver-Russell syndrome
The first 2 years of recombinant growth hormone therapy offers significant benefits for prepubertal children with Silver–Russell syndrome, French researchers have found.
Plasma and urine testing both ‘reliable’ for paediatric PPGL diagnosis
Plasma and urine analyses are both reliable screening tests for the diagnosis of phaeochromocytoma/paraganglioma in children and adolescents, report researchers in Clinical Endocrinology.
Real-word support for rhIGF-1 treatment in adolescents with severe growth failure
Treatment with recombinant human insulin-like growth factor-1 enables children and adolescents with severe growth failure due to primary IGF-1 deficiency to reach near-adult height, suggest real-world registry data.
AI-assisted tool aids paediatric achondroplasia growth calculations
An artificial intelligence-assisted tool can speed up anthropometric calculations for paediatric endocrinologists monitoring growth in children with achondroplasia, research indicates.
Genetic causes identified for nonfamilial tall stature in childhood
Genetic testing has identified a likely cause for nonfamilial tall stature in 11% of children examined, show study findings published in the European Journal of Pediatrics.
Growth hormone therapy response confirmed for children with heterozygous NPR2 alterations
Research from the Netherlands suggests that the majority of children heterozygous for pathogenic alterations to the NPR2 gene, resulting in mild skeletal dysplasia, respond to growth hormone therapy.
