Achondroplasia guidelines outline UK multidisciplinary care throughout childhood
The UK Achondroplasia Network has developed consensus guidelines on multidisciplinary care of children and young people with achondroplasia from diagnosis until adulthood.
SGA impaired glucose metabolism exacerbated by growth hormone therapy
Glucose–insulin impairment in small-for-gestational-age children is comparable to that found in children with obesity and worsened by use of growth hormone therapy, say German researchers.
European guidance released for childhood adrenal, extra-adrenal paraganglioma care
A European Standard Clinical Practice Guidance has been published in the European Journal of Endocrinology on the diagnosis and treatment of adrenal and extra-adrenal paragangliomas in children and adolescents.
Navepegritide APPROACH improves height velocity for children with achondroplasia
Treatment with a C-type natriuretic peptide prodrug significantly increases annualised growth velocity in children with achondroplasia and offers additional health benefits, say the APPROACH trial investigators.
CAH-specific growth charts aid clinical management during childhood
US researchers have created age- and sex-adjusted growth charts for use in children with classic congenital adrenal hyperplasia, reflecting the distinct patterns of height and weight among patients versus the general population.
Noonan syndrome consensus statements guide lifelong care
Italian clinicians have published a set of consensus statements on the multidisciplinary diagnosis, care and treatment of patients with Noonan syndrome from childhood and beyond.
Age at childhood differentiated thyroid cancer diagnosis linked to disease severity
Earlier age at diagnosis of childhood differentiated thyroid cancer is associated with a greater risk of advanced disease, but overall, patients have excellent long-term survival irrespective of age, stage, and treatment response, US study findings indicate.
Study highlights anti-fracture drug underuse in osteogenesis imperfecta
Children with osteogenesis imperfecta are more likely to use anti-fracture drugs than their older counterparts, but underuse is common across all age groups, US study findings indicate.
Early growth hormone offers height and nutritional benefits in Silver-Russell syndrome
The first 2 years of recombinant growth hormone therapy offers significant benefits for prepubertal children with Silver–Russell syndrome, French researchers have found.
Plasma and urine testing both ‘reliable’ for paediatric PPGL diagnosis
Plasma and urine analyses are both reliable screening tests for the diagnosis of phaeochromocytoma/paraganglioma in children and adolescents, report researchers in Clinical Endocrinology.
