Patients with congenital adrenal hyperplasia are significantly more likely to be admitted to hospital and experience severe in-hospital outcomes than people without the condition, especially during the first years of life, highlight Swiss researchers.
Simvastatin treatment has not significantly improved growth in a randomised phase 3 trial of children with Noonan syndrome (NS), French researchers report in eClinicalMedicine.
The TRANSECEND trial confirms that the melanocortin-4 receptor agonist setmelanotide achieves a significantly greater reduction in BMI and hunger than placebo in children, adolescents and adults with acquired hypothalamic obesity.
The Endocrine Society has published a clinical practice guideline on the diagnosis and treatment of children with central precocious puberty in The Journal of Clinical Endocrinology & Metabolism.
International guidance has been published on managing the transition of children with endocrine disorders from paediatric to adult services, and on the use of genetic testing in children with short stature.
Burosumab treatment for X-linked hypophosphataemia may begin in the first year of life, suggest phase 2 trial findings published in The Lancet Diabetes & Endocrinology.
UK study findings indicate that a slow-release formulation of the gonadotropin-releasing hormone analogue triporelin given every 24 weeks is as effective as the standard 12-weekly treatment for central precocious puberty.
The UK Achondroplasia Network has developed consensus guidelines on multidisciplinary care of children and young people with achondroplasia from diagnosis until adulthood.
A European Standard Clinical Practice Guidance has been published in the European Journal of Endocrinology on the diagnosis and treatment of adrenal and extra-adrenal paragangliomas in children and adolescents.
US researchers have created age- and sex-adjusted growth charts for use in children with classic congenital adrenal hyperplasia, reflecting the distinct patterns of height and weight among patients versus the general population.
