The C-type natriuretic peptide analogue vosoritide significantly increases the growth rate of children with achondroplasia, indicate the results of a randomised, double-blind phase 3 study published in The Lancet.
Less than 10% of brain magnetic resonance imaging scans in children with isolated growth hormone deficiency reveal a pathological cause, say researchers.
Receiving treatment with recombinant human growth hormone in childhood is unlikely to be associated with an increased risk for mortality in the long term, show the results of the full SAGhE cohort.
Severe growth hormone deficiency can be detected with high accuracy using newborn screening cards, suggest researchers who recommend a diagnostic GH cutoff of less than 7 µg/L.
Researchers confirm that pubertal timing in girls is most strongly influenced by that of their mothers, whereas for boys their fathers have the stronger influence.