Over a third of children diagnosed with congenital hypothyroidism have discontinued treatment within 10 years of diagnosis, say French researchers who have identified predictive markers for a transient prognosis.
Levo-thyroxine dose may need more initial adjustment with solution than pills in congenital hypothyroidism
Children using an oral solution of levo-thyroxine for treatment of congenital hypothyroidism may require closer monitoring during the first few months than those using tablet formulations, say researchers.
Researchers find that teenagers with endocrine disorders often have gaps in their knowledge of their condition and how to manage it, making them poorly prepared for transition to adult clinic.
Listen to Dr Salvatore Vaccarella discussing his recent research demonstrating the likelihood of thyroid cancer overdiagnosis in children and adolescents.
Effective detection of newborn babies with congenital hypothyroidism requires a repeat screen with a lower thyroid-stimulating hormone cutoff for at-risk infants, research suggests.
A randomised trial of children receiving treatment for thyrotoxicosis shows no difference in biochemical stability between block-and-replace and dose-titration strategies.
Following the publication of the long-term mortality findings of the SAGhE consortium, we discuss the safety profile of growth hormone with consortium member Stefano Cianfarani.
Primary ovarian insufficiency affects the majority of girls with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, in most cases occurring before they have attained their final adult height, show data from a national cohort.
An extensive multinational study of patients with disordered thyroid hormone transport due to MCT8 deficiency has identified key characteristics that could help early diagnosis and the treatment of underlying risk factors associated with a poor outcome in affected patients.
Factors including age at diagnosis and the specific disease influence the likelihood of children with chronic endocrine conditions being lost to follow-up, show French study findings.