Less than 10% of brain magnetic resonance imaging scans in children with isolated growth hormone deficiency reveal a pathological cause, say researchers.
Receiving treatment with recombinant human growth hormone in childhood is unlikely to be associated with an increased risk for mortality in the long term, show the results of the full SAGhE cohort.
Girls with Turner syndrome are less prepared for transition to adult medical care than other patients with long-term health issues and may benefit from additional support, say Austrian researchers.
Severe growth hormone deficiency can be detected with high accuracy using newborn screening cards, suggest researchers who recommend a diagnostic GH cutoff of less than 7 µg/L.
Children with idiopathic growth hormone deficiency should be retested at mid-puberty, say researchers who found a substantial proportion no longer required growth hormone treatment.
Researchers have identified 10 novel single nucleotide polymorphisms that may help to predict the risk for familial short stature in Han Chinese children.
A case series illustrates the highly variable phenotypes of patients with congenital hypopituitarism caused by SOX3 duplication, and strengthens the association with neural tube defects.
Children with familial short stature (FSS) who have mutations in their C-type natriuretic peptide receptor (NPR2) gene may respond well to growth hormone (GH) therapy, preliminary study findings indicate
Factors including age at diagnosis and the specific disease influence the likelihood of children with chronic endocrine conditions being lost to follow-up, show French study findings.
Childhood cancer survivors and endocrinopathies – the need for oncologist and endocrinologist collaboration
Dr Sogol Mostoufi focuses on the treatment-related endocrine side effects commonly experienced by childhood cancer survivors, and the need for screening, life-long follow-up and treatment in this high-risk population.