A single measurement of plasma levels of a fragment of type X collagen may give an instant picture of how fast a child is growing, say researchers.
Rare copy number variants have been identified in a study of children who have growth hormone insensitivity or insulin-like growth factor-1 insensitivity, shedding light on the genetic basis of their conditions.
Dr Cheri Deal discusses the use of growth hormone in children with Prader-Willi syndrome, the importance of multidisciplinary care and the future of treatment for this genetic condition.
Following the publication of the long-term mortality findings of the SAGhE consortium, we discuss the safety profile of growth hormone with consortium member Stefano Cianfarani.
Children who receive total body irradiation or craniospinal radiation for cancer may have a reduced response to growth hormone therapy if they later require it, say researchers.
Less than 10% of brain magnetic resonance imaging scans in children with isolated growth hormone deficiency reveal a pathological cause, say researchers.
Receiving treatment with recombinant human growth hormone in childhood is unlikely to be associated with an increased risk for mortality in the long term, show the results of the full SAGhE cohort.
Girls with Turner syndrome are less prepared for transition to adult medical care than other patients with long-term health issues and may benefit from additional support, say Austrian researchers.
Severe growth hormone deficiency can be detected with high accuracy using newborn screening cards, suggest researchers who recommend a diagnostic GH cutoff of less than 7 µg/L.
Children with idiopathic growth hormone deficiency should be retested at mid-puberty, say researchers who found a substantial proportion no longer required growth hormone treatment.