An oral growth hormone secretagogue receptor agonist produces larger GH responses than standard stimulation tests in children with growth hormone deficiency, study findings suggest.
A study of Brazilian children with isolated SHOX haploinsufficency who were followed up until adult height has demonstrated a long-term benefit of recombinant human growth hormone therapy with or without puberty modulator treatment.
A 4-year-old girl is referred to the local paediatric endocrine unit with signs of pubertal development.
Children’s weight trajectories between birth and 4 years of age are associated with their dehydroepiandrosterone sulphate levels at age 7 years, study findings show.
A large study shows that growth in the first 5 years of life is associated with age at pubertal onset.
Blood-cell markers of inflammation are elevated in children with Cushing’s syndrome and may offer useful diagnostic information, say researchers.
Researchers recommend next-generation sequencing for the first-line diagnosis of patients with 46,XY differences of sex development.
Steroid hormone profiles can identify the majority of children with non-congenital adrenal hyperplasia primary adrenal insufficiency, say researchers.
Treatment with recombinant human growth hormone is not associated with cardiovascular adverse events in clinical practice, show data from two large, multicentre cohorts.
Young children with short stature due to aggrecan deficiency achieve a marked improvement in height velocity during their first year of treatment with recombinant human growth hormone, shows a cohort study.