Recombinant human growth hormone appears to have a positive effect on growth in children with Kabuki Syndrome, shows an open-label study.
A cohort study of healthy infants has characterised the relationships between circulating levels of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 and changes in body length and weight in the first year of life.
A phase 2 study of macimorelin in children with suspected growth hormone deficiency shows similar results to those established in adults.
The human leukocyte antigen polymorphisms that increase the risk of type 1 diabetes are linked to growth and insulin-like growth factor-I levels during infancy, say researchers.
The heiGHt Trial investigators report that once-weekly treatment with lonapegsomatropin offers noninferior and indeed superior annualised height velocity to that achieved with daily somatropin for children with growth hormone deficiency.
Researchers have found a large variety of genetic diagnoses in children with short stature investigated for suspected growth hormone insensitivity.
A long-term follow-up study of children with Prader-Willi syndrome has found no evidence to indicate that growth hormone therapy affects the risk or severity of scoliosis in this population.
Researchers find that teenagers with endocrine disorders often have gaps in their knowledge of their condition and how to manage it, making them poorly prepared for transition to adult clinic.
A polygenic risk score for height can predict a child’s adult height with similar accuracy to their mid-parental height, say researchers.