Retrospective diagnosis of Turner syndrome using electronic health records or screening at initial assessment
Children who are born small for gestational age and have syndromic short stature of unknown cause should be tested for genetic abnormalities using whole-exome sequencing researchers suggest.
Children with growth hormone deficiency receiving once-weekly TransCon human growth hormone achieve a significantly greater annualised height velocity than those receiving daily somatropin, results from the heiGHt trial show.
The type 1 diabetes genetic risk score differentiates between patients with monogenic and polygenic autoimmune diabetes and can thus be used to aid the discovery of novel genes associated with the monogenic form.
Plasma concentrations of the adrenal-derived 11-oxygenated-C19 androgen 11-ketotestosterone strongly correlate with salivary levels in children with congenital adrenal hyperplasia, UK researchers report.
A once-daily regimen of the thyroid hormone analogue Triac normalised serum levels of tri-iodothyronine in a phase II trial of paediatric and adult patients with transporter monocarboxylate transporter 8 deficiency.
Growth hormone deficiency is common among childhood cancer survivors and is associated with the use of hypothalamic-pituitary radiotherapy, alkylating agents and intrathecal chemotherapy, as well as adverse health outcomes, say researchers.
The prevalence of overweight and obesity remains high among European children, say researchers, with “worrisome” rising trends in some countries, despite stabilising rates and downwards trends in other countries.
A Swedish study suggests that, as with girls, puberty has shifted to begin at an earlier age in boys.
Data from two large observational studies show that children treated in the USA receive a higher dose of the commercial growth hormone somatropin and are taller, older, and more likely to be boys than girls relative to those treated in Europe.