A Swedish study suggests that, as with girls, puberty has shifted to begin at an earlier age in boys.
Data from two large observational studies show that children treated in the USA receive a higher dose of the commercial growth hormone somatropin and are taller, older, and more likely to be boys than girls relative to those treated in Europe.
Prepubertal children with type 1 diabetes have greater variability in their blood glucose levels than older children, research suggests.
Daily treatment with subcutaneous vosoritide leads to a sustained increase in annualised growth velocity, with generally mild side effects, in children with achondroplasia, show data published in The New England Journal of Medicine.
The latest TODAY2 findings show rapid accumulation of cardiovascular risk factors and diabetes complications following a diagnosis of type 2 diabetes during childhood or adolescence.
The risk of a false–positive result on a low-dose adrenocorticotropic hormone stimulation test can be reduced in children by measuring cortisol levels at three consecutive time points instead of just one, researchers say.
Researchers have defined urinary steroid metabolite levels that indicate inadequate and excessive adrenal suppression for children with congenital adrenal hyperplasia undergoing glucocorticoid treatment.
Individuals with Noonan syndrome harbouring pathogenic variations in the PTPN11 gene respond well to treatment with recombinant human growth hormone, retrospective study data show.
Higher chance of diabetes remission but more reoperations for adolescents 5 years after bariatric surgery
The 5-year outcomes of the Teen-LABS cohort show that adolescents who undergo bariatric surgery have a good chance of achieving diabetes remission, but may require more reoperations than adult patients.
The randomised Ellipse trial has demonstrated significant blood glucose reductions with the glucagon-like peptide-1 receptor agonist liraglutide in children and adolescents with type 2 diabetes already taking metformin.