Weight gain in infancy linked to increased mid-childhood adrenal androgen levels
Children’s weight trajectories between birth and 4 years of age are associated with their dehydroepiandrosterone sulphate levels at age 7 years, study findings show.
Children’s weight trajectories between birth and 4 years of age are associated with their dehydroepiandrosterone sulphate levels at age 7 years, study findings show.
A large study shows that growth in the first 5 years of life is associated with age at pubertal onset.
Blood-cell markers of inflammation are elevated in children with Cushing’s syndrome and may offer useful diagnostic information, say researchers.
Researchers recommend next-generation sequencing for the first-line diagnosis of patients with 46,XY differences of sex development.
Steroid hormone profiles can identify the majority of children with non-congenital adrenal hyperplasia primary adrenal insufficiency, say researchers.
The 3-year findings of the REAL 3 trial show that weekly somapacitan continued to deliver equivalent height gains and safety results to that achieved with standard daily recombinant human growth hormone treatment in children with growth hormone deficiency.
Treatment with recombinant human growth hormone is not associated with cardiovascular adverse events in clinical practice, show data from two large, multicentre cohorts.
Young children with short stature due to aggrecan deficiency achieve a marked improvement in height velocity during their first year of treatment with recombinant human growth hormone, shows a cohort study.
Over a third of children diagnosed with congenital hypothyroidism have discontinued treatment within 10 years of diagnosis, say French researchers who have identified predictive markers for a transient prognosis.
The likelihood of finding an underlying genetic cause of short stature in children is markedly increased if they have additional factors such as dysmorphic facial features or skeletal dysplasia, say researchers.