The 5-year outcomes of the Teen-LABS cohort show that adolescents who undergo bariatric surgery have a good chance of achieving diabetes remission, but may require more reoperations than adult patients.
The randomised Ellipse trial has demonstrated significant blood glucose reductions with the glucagon-like peptide-1 receptor agonist liraglutide in children and adolescents with type 2 diabetes already taking metformin.
Data from clinical practice support the option of adding gonadotrophin-releasing hormone analogue to growth hormone therapy in some clinical situations to extend the treatment window and optimise final height in children with idiopathic short stature.
Delayed puberty is common in the developed world, affecting over 2% of adolescents, and is associated with adverse health outcomes including short stature, reduced bone mineral density and compromised psychosocial health.
This year the Insight for MAnaging Growth for Endocrine nurses (IMAGE) conference will be held on 10-11th October 2019 at the Radison Blu Hotel, Bordeaux, France, The aims of the symposium are to pr [...]
In our first edition, Professor Frederic Castinetti discussing the results of an international collaboration to study the natural history and treatment outcomes of multiple endocrine neoplasia type 2B, and Professor Martin Savage comments on a randomized trial of letrozole versus testosterone in boys with constitutional delay of growth and puberty.
A study of patients with mutations or terminal deletions in the insulin-like growth factor 1 receptor gene shows that the majority are small for gestational age, short and microcephalic, with an elevated serum IGF-1 level.
Research shows that growth hormone deficiency and central precocious puberty can occur in children several years after traumatic brain injury (TBI), even among those with normal pituitary function 1 year after the event.
Basal adrenal androgen levels can help identify girls with non-classical congenital adrenal hyperplasia who present as central precocious puberty, but adrenocorticotrophic hormone stimulation may be needed for a firm diagnosis, say researchers.