Paediatric Endocrinology

01 April 2018
medwireNews: The research to date suggests that hormonal treatments achieve the intended physical results in transgender adolescents, but the evidence quality is low and psychosocial issues are barely addressed, say the authors of a systematic review. Denise Chew (University of Melbourne, Victoria, Australia) and co-workers identified a total... Read More
01 April 2018
medwireNews: Surgical treatment of severely obese adolescents with type 2 diabetes is associated with better glycaemic control and a greater reduction in BMI than medical management, US researchers report. Bariatric surgery also resulted in reduced cardiovascular risk markers and improved kidney function whereas treatment with metformin alone... Read More
01 March 2018
medwireNews: Researchers suggest that obesity could be a factor triggering some girls with premature thelarche to develop precocious or rapidly progressive puberty. The team found that the majority of patients in their study who progressed were older than 2 years of age when their symptoms first appeared, and that these patients had a... Read More
01 March 2018
medwireNews: Hypoglycaemia is a relatively frequent and serious finding in patients with congenital adrenal hyperplasia (CAH) during an adrenal crisis, and can be fatal, say Japanese researchers. The team reports that hypoglycaemia was present in 29% of 53 CAH patients who had an adrenal crisis. These patients were among 378 identified in a... Read More
01 February 2018
medwireNews: The benefits of prompt growth hormone (GH) treatment are apparent even in patients diagnosed as deficient at a very young age, a study suggests. The researchers also found that treatment response differed according to whether the patients had multiple pituitary hormone deficiency (MPHD) or isolated GH deficiency (IGHD). And they... Read More
01 February 2018
medwireNews: Treating patients with congenital hypothyroidism with a high dose of levothyroxine (LT4) from infancy does not compromise their IQ in young adulthood, report researchers. The 76 patients (68% female) in the study had received an average LT4 dose of 13.5 µg/kg per day (ranging from 4.4 to 20.8 µg/kg per day), starting at a median... Read More