Paediatric Endocrinology

01 October 2018
medwireNews: Boys who have normal or minor abnormalities of their external genitalia despite a 45,X/46,XY karyotype have complications including reduced fertility, report researchers. “Therefore, it seems essential to identify these patients by considering the systematic evaluation of karyotype in patients referred for growth failure... Read More
30 September 2018
medwireNews: Skewed inactivation of the X chromosome may underlie a proportion of cases of autoimmune thyroid disease (ATD) in girls, research suggests. The study by Preamrudee Poomthavorn (Mahidol University, Bangkok, Thailand) and team included 83 patients (57 with Graves’ disease and 26 with Hashimoto thyroiditis), who were diagnosed at a... Read More
31 August 2018
medwireNews: Impaired glucose tolerance in obese youths frequently reverts to normal, although the chances of this happening are strongly influenced by ethnicity, researchers report in The Lancet Child & Adolescent Health. However, reverting to normal glucose tolerance was associated with a significant increase in the oral... Read More
31 August 2018
medwireNews: Very young children with Prader–Willi syndrome continue to accrue mental and motor development benefits during 3 years of treatment with growth hormone (GH), say researchers. Stephany Donze (Dutch Growth Research Foundation, Rotterdam) and colleagues previously found that 1 year of GH treatment improved these outcomes in a... Read More
31 July 2018
medwireNews: The Endocrine Society has released a guideline for the diagnosis and treatment of hypothalamic–pituitary and growth disorders in survivors of childhood cancer. Charles Sklar (Memorial Sloan-Kettering Cancer Center, New York, USA) and guideline co-authors note that 40–50% of childhood cancer survivors “will develop at least one... Read More
31 July 2018
medwireNews: Patients with Silver–Russell syndrome experience issues with their appearance and with social interactions, as well as with their height, show findings from an interview-based study. Lisa Marie Ballard (University of Southampton, UK) and colleagues interviewed 15 patients with Silver–Russell syndrome – all adults at the time –... Read More