Paediatric Endocrinology

30 June 2017
medwireNews: A randomised controlled trial shows some benefit of metformin treatment in prepubertal children with obesity, but not in pubertal participants. Among the prepubertal children, the 33 who completed 6 months of treatment with metformin 500 mg twice daily had a body mass index (BMI) z score reduction from 3.4 to 2.6, which... Read More
30 June 2017
medwireNews: Sequencing selected genes of patients referred for genetic testing for Silver Russell Syndrome (SRS) can identify those with diagnoses requiring a markedly different management strategy, report researchers. Targeted sequencing allowed Thomas Eggermann (Technical University Aachen, Germany) and study co-authors to make differential... Read More
01 June 2017
medwireNews: Researchers have found that compounded hydrocortisone capsules used to treat congenital adrenal hyperplasia (CAH) and other causes of adrenal insufficiency in children contain inconsistent amounts of the hormone, highlighting the need for licensed paediatric formulations. Oliver Blankenstein (Charité-Universitätsmedizin Berlin,... Read More
01 June 2017
medwireNews: Levels of thyroid hormones, specifically free tri-iodothyronine (FT3), change markedly during childhood, data from a large prospective study show. The findings emerge from an analysis of children in the Avon Longitudinal Study of Parents and Children – 4442 with thyroid function tests at age 7 years and 1263 with tests at age 15... Read More
28 April 2017
medwireNews: Metabolic changes in transgender adolescents receiving cross-sex hormone therapy are consistent with those previously reported in adults and support the short-term safety of the treatment, say researchers. Jason Jarin (University of Texas Southwestern, Dallas, USA) and study co-authors assessed data from 116 adolescents who... Read More
28 April 2017
medwireNews: Cognitive behavioural therapy (CBT) may be a more effective intervention than non-directive, supportive counselling for adolescents with type 1 diabetes who struggle with glycaemic control, a randomised control trial shows. The researchers found that glycated haemoglobin (HbA1c) levels remained stable in patients given CBT,... Read More