Paediatric Endocrinology

30 November 2018
medwireNews: Tongue lesions, gastrointestinal problems and musculoskeletal complaints are the most common symptoms for which children are investigated in the years leading up to a multiple endocrine neoplasia type 2B (MEN2B) diagnosis, say researchers. “An index of suspicion for MEN2B should be maintained when evaluating patients with a... Read More
30 November 2018
medwireNews: Established genetic risk factors for adult-onset Graves’ disease apply equally in patients with a diagnosis in childhood, say researchers. However, they also show that having more risk alleles for some of these variants may be associated with an earlier onset age. Aleksander Kuś (Medical University of Warsaw, Poland) and co-... Read More
01 November 2018
medwireNews: The Endocrine Society has released updated guidelines for the management of congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase deficiency. The guidelines, which are published in The Journal of Clinical Endocrinology & Metabolism, contain several changes from the preceding version, published in... Read More
01 November 2018
medwireNews: Children who start to gain weight in their preschool years are at the highest risk of being obese in adolescence, shows a study in The New England Journal of Medicine. “The probability that young children who are obese will return to a normal weight in adolescence appears to be less than 20% and decreases further with age... Read More
01 October 2018
medwireNews: Boys who have normal or minor abnormalities of their external genitalia despite a 45,X/46,XY karyotype have complications including reduced fertility, report researchers. “Therefore, it seems essential to identify these patients by considering the systematic evaluation of karyotype in patients referred for growth failure... Read More
30 September 2018
medwireNews: Skewed inactivation of the X chromosome may underlie a proportion of cases of autoimmune thyroid disease (ATD) in girls, research suggests. The study by Preamrudee Poomthavorn (Mahidol University, Bangkok, Thailand) and team included 83 patients (57 with Graves’ disease and 26 with Hashimoto thyroiditis), who were diagnosed at a... Read More