News

30 November 2017
medwireNews: Heterozygous mutations in the Indian hedgehog gene (IHH) are a potential cause of idiopathic short stature (ISS), say researchers who report that children with these mutations appear to respond well to treatment with recombinant human growth hormone (rhGH). The researchers say their work has “extended the known phenotype... Read More
30 November 2017
medwireNews: Findings from a database analysis suggest that salt supplementation may not influence medication doses or height and weight in infants with congenital adrenal hyperplasia (CAH). The study, which is published in Hormone Research in Paediatrics, included data from 311 patients (153 female, 205 male) with salt-wasting CAH,... Read More
30 November 2017
medwireNews: Using the Worldwide Pediatric Consensus (PedC) criteria reduces the proportion of adolescent girls diagnosed with polycystic ovarian morphology (PCOM) but does not identify those with polycystic ovarian syndrome (PCOS), say researchers. The PedC criteria advise a diagnosis of PCOM in adolescents when ovarian volume is larger than... Read More
30 October 2017
medwireNews: Factors including age, thyroid hormone levels and weight loss prior to diagnosis influence whether children gain weight after being treated for Graves’ disease, study results show. Perrin White (University of Texas Southwestern Medical Center, Dallas, USA) and co-researchers found that 222 paediatric patients with Graves’ disease... Read More
30 October 2017
medwireNews: Higher doses of vitamin D3 than currently recommended may be needed to achieve vitamin D sufficiency in schoolchildren living at northern latitudes, show the results of a randomised trial. However, the researchers stress that all three supplemental doses used – 600, 1000 or 2000 IU/day for 6 months – prevented severe vitamin D... Read More
30 October 2017
medwireNews: Factors including age at initiation of growth hormone (GH) therapy and severity of inflammation during treatment determine whether children with juvenile idiopathic arthritis (JIA) will achieve a favourable growth outcome, study results show. The researchers stress that “clinical monitoring of growth remains crucial”, because the... Read More