Plasma concentrations of the adrenal-derived 11-oxygenated-C19 androgen 11-ketotestosterone strongly correlate with salivary levels in children with congenital adrenal hyperplasia, UK researchers report.
A Swedish study suggests that, as with girls, puberty has shifted to begin at an earlier age in boys.
Daily treatment with subcutaneous vosoritide leads to a sustained increase in annualised growth velocity, with generally mild side effects, in children with achondroplasia, show data published in The New England Journal of Medicine.
Researchers have defined urinary steroid metabolite levels that indicate inadequate and excessive adrenal suppression for children with congenital adrenal hyperplasia undergoing glucocorticoid treatment.
medwireNews goes behind the headlines, talking to researchers and independent experts about how the latest findings will impact clinicians caring for children with endocrine disorders.