News

31 December 2018
medwireNews: Researchers report sustained improvements in skeletal mineralisation, along with other benefits including improved growth and respiratory function, in children with life-threatening perinatal or infantile hypophosphatasia during 7 years of treatment with asfotase alfa. The current findings, reported by Michael Whyte (Shriners... Read More
31 December 2018
medwireNews: Most children continue on a normal growth trajectory if their recombinant human growth hormone (GH) dose is reduced by half after they have achieved catch-up growth, shows a randomised trial. Considering the long duration of GH treatment, “the ultimate goal” after children have achieved catch-up growth should be to use the lowest... Read More
31 December 2018
medwireNews: Rare forms of maturity onset diabetes of the young (MODY) are frequently misdiagnosed as type 1 or even type 2 diabetes, say researchers, despite patients presenting with distinct characteristics. Katharina Warncke (Technische Universität München, Germany) and co-researchers found that 38% of patients were initially misdiagnosed,... Read More
30 November 2018
medwireNews: Tongue lesions, gastrointestinal problems and musculoskeletal complaints are the most common symptoms for which children are investigated in the years leading up to a multiple endocrine neoplasia type 2B (MEN2B) diagnosis, say researchers. “An index of suspicion for MEN2B should be maintained when evaluating patients with a... Read More
30 November 2018
medwireNews: Adherence to recombinant human growth hormone (GH) has a strong influence on the growth response of children with GH deficiency, especially during the second year of treatment, report researchers. The findings emerge from an analysis of 95 prepubertal participants of the easypod Connect observational study (ECOS) who had complete... Read More
30 November 2018
medwireNews: Established genetic risk factors for adult-onset Graves’ disease apply equally in patients with a diagnosis in childhood, say researchers. However, they also show that having more risk alleles for some of these variants may be associated with an earlier onset age. Aleksander Kuś (Medical University of Warsaw, Poland) and co-... Read More