News

01 October 2018
medwireNews: Boys who have normal or minor abnormalities of their external genitalia despite a 45,X/46,XY karyotype have complications including reduced fertility, report researchers. “Therefore, it seems essential to identify these patients by considering the systematic evaluation of karyotype in patients referred for growth failure... Read More
30 September 2018
medwireNews: Two reports from the GeNeSIS observational study reveal the latest growth data and confirm that the safety profile of recombinant human growth hormone (rhGH) “remains favourable”. However, Christopher Child (Eli Lilly and Company, Windlesham, UK) and study co-authors note in The Journal of Clinical Endocrinology &... Read More
30 September 2018
medwireNews: Skewed inactivation of the X chromosome may underlie a proportion of cases of autoimmune thyroid disease (ATD) in girls, research suggests. The study by Preamrudee Poomthavorn (Mahidol University, Bangkok, Thailand) and team included 83 patients (57 with Graves’ disease and 26 with Hashimoto thyroiditis), who were diagnosed at a... Read More
31 August 2018
medwireNews: Very young children with Prader–Willi syndrome continue to accrue mental and motor development benefits during 3 years of treatment with growth hormone (GH), say researchers. Stephany Donze (Dutch Growth Research Foundation, Rotterdam) and colleagues previously found that 1 year of GH treatment improved these outcomes in a... Read More
31 August 2018
medwireNews: Impaired glucose tolerance in obese youths frequently reverts to normal, although the chances of this happening are strongly influenced by ethnicity, researchers report in The Lancet Child & Adolescent Health. However, reverting to normal glucose tolerance was associated with a significant increase in the oral... Read More
31 August 2018
medwireNews: The SYNERGY trial investigators report significant improvements in height velocity in South Korean children with idiopathic short stature (ISS) treated with daily recombinant human growth hormone (rhGH). During the first 6 months of treatment, the average height velocity increased from 5.63 cm/year to 10.08 cm/year in 59 children... Read More