News

30 June 2017
medwireNews: Weekly injection of a pegylated recombinant human growth hormone (PEG-rhGH) has proved effective in a study of Chinese children with GH deficiency (GHD). The publication details results from a phase II study, which established the superiority of the 0.2 mg/kg per week dose over the 0.1 mg/kg per week dose, and of a phase III study... Read More
30 June 2017
medwireNews: A randomised controlled trial shows some benefit of metformin treatment in prepubertal children with obesity, but not in pubertal participants. Among the prepubertal children, the 33 who completed 6 months of treatment with metformin 500 mg twice daily had a body mass index (BMI) z score reduction from 3.4 to 2.6, which... Read More
30 June 2017
medwireNews: Sequencing selected genes of patients referred for genetic testing for Silver Russell Syndrome (SRS) can identify those with diagnoses requiring a markedly different management strategy, report researchers. Targeted sequencing allowed Thomas Eggermann (Technical University Aachen, Germany) and study co-authors to make differential... Read More
01 June 2017
medwireNews: Researchers have found that compounded hydrocortisone capsules used to treat congenital adrenal hyperplasia (CAH) and other causes of adrenal insufficiency in children contain inconsistent amounts of the hormone, highlighting the need for licensed paediatric formulations. Oliver Blankenstein (Charité-Universitätsmedizin Berlin,... Read More
01 June 2017
medwireNews: Levels of thyroid hormones, specifically free tri-iodothyronine (FT3), change markedly during childhood, data from a large prospective study show. The findings emerge from an analysis of children in the Avon Longitudinal Study of Parents and Children – 4442 with thyroid function tests at age 7 years and 1263 with tests at age 15... Read More
01 June 2017
medwireNews: A substantial proportion of children with isolated growth hormone deficiency (IGHD) have a normal result when retested just 1 year later, report researchers. By contrast, all the 95 patients in their study who had multiple pituitary hormone deficiency still had a subnormal GH stimulation response when retested after 1 year of GH... Read More