Growth Disorders

30 November 2016
medwireNews: A study details the clinical characteristics of patients who have autosomal dominant short stature caused by heterozygous mutations in the aggrecan gene (ACAN). Patients with the condition frequently have advanced bone age, and joint and back problems are common, the researchers report in The Journal of Clinical... Read More
28 October 2016
medwireNews: French researchers have characterised the associations between gender, genotype and phenotype in a cohort of patients with mutations affecting the SHOX (short stature homeobox gene) region. “Our analysis confirms the higher penetrance and the different expression of SHOX rearrangements in females compared to... Read More
30 September 2016
medwireNews: A candidate gene approach does not identify a panel of genes that can predict the growth response to recombinant human growth hormone (rhGH) better than clinical factors alone, show the findings of the PREDICT validation study. The validation study included 293 patients with growth hormone deficiency (GHD) and 132 with Turner... Read More
12 September 2016
The final day of the 2016 ESPE conference featured more original research communications, symposia and the final two plenary lectures. Long-acting growth hormone: a crowded field? Long-acting growth hormone is getting ever closer to the clinic, with one late-breaking trial plus several presentations in one of the morning’s free communication... Read More
11 September 2016
The second day of ESPE saw the first of the free communication sessions, with researchers presenting their latest findings. A first-line medical option for acromegaly In a well-attended session on pituitary research, Cecile Thomas-Teinturier (Hôpital de Bicétre, Paris, France) reported that pegvisomant treatment produced “drastic decreases” in the... Read More
10 September 2016
Saturday 10th September The 2016 European Society of Paediatric Endocrinology (ESPE) conference kicked off this morning with the ESPE Working Groups, covering gynaecology, diabetes technology and therapeutics, Turner syndrome, bone and growth plate, and disorders of sexual development. Exploring Turner syndrome The Turner syndrome... Read More