Growth Disorders

30 October 2017
medwireNews: Factors including age at initiation of growth hormone (GH) therapy and severity of inflammation during treatment determine whether children with juvenile idiopathic arthritis (JIA) will achieve a favourable growth outcome, study results show. The researchers stress that “clinical monitoring of growth remains crucial”, because the... Read More
29 September 2017
medwireNews: A study confirms the presence of impaired cardiac performance, body composition and cardiopulmonary function in children with growth hormone deficiency (GHD), all of which are reversed by GH replacement. Mariacarolina Salerno (Federico II University, Naples, Italy) and colleagues studied 17 boys and four girls with untreated GHD,... Read More
31 August 2017
medwireNews: Findings from the real-world NordiNet® International Outcome Study demonstrate clear benefits of early diagnosis and treatment initiation in patients with isolated growth hormone deficiency (GHD). However, Michel Polak (Hôpital Universitaire Necker Enfants Malades, Paris, France) and study co-authors stress that all patients... Read More
28 July 2017
medwireNews: Data from a dose-escalation study of the long-acting growth hormone (GH) somapacitan support its further development as a weekly treatment in children with GH deficiency (GHD), say researchers. The medication, which is currently being tested in a phase III trial in adults and a phase II trial in children, reversibly binds to... Read More
30 June 2017
medwireNews: Weekly injection of a pegylated recombinant human growth hormone (PEG-rhGH) has proved effective in a study of Chinese children with GH deficiency (GHD). The publication details results from a phase II study, which established the superiority of the 0.2 mg/kg per week dose over the 0.1 mg/kg per week dose, and of a phase III study... Read More
01 June 2017
medwireNews: A substantial proportion of children with isolated growth hormone deficiency (IGHD) have a normal result when retested just 1 year later, report researchers. By contrast, all the 95 patients in their study who had multiple pituitary hormone deficiency still had a subnormal GH stimulation response when retested after 1 year of GH... Read More