Growth Disorders

31 July 2018
medwireNews: Real-time data on treatment adherence show its importance for good growth outcomes in patients taking recombinant human growth hormone (GH). Ekaterina Koledova (Merck Serono SA, Darmstadt, Germany) and colleagues made use of data from 1190 patients in the easypod™ connect observational study (ECOS), a register of patients using... Read More
01 June 2018
medwireNews: Growth hormone (GH) therapy has a greater impact on the metabolic outcomes of girls than boys, research suggests. This may indicate that girls with GH deficiency (GHD) should be more closely monitored during GH treatment, with the aim of modifying their lifestyles to counteract the metabolic changes, say Carla Giordano and co-... Read More
01 May 2018
medwireNews: Obese children with reduced peak stimulated growth hormone (GH) are likely to have hyperuricaemia, along with markers of increased cardiovascular risk, research shows. Peak GH in response to the arginine-levodopa stimulation test was markedly lower in the 78 obese children and adolescents in the study (average BMI standard... Read More
01 April 2018
medwireNews: Analysis of data from the NordiNet® International Outcome Study highlights continued delays in treating children with growth hormone deficiency (GHD) and the use of suboptimal doses in patients with Turner syndrome (TS). Researchers led by Michel Polak (Hôpital Universitaire Necker Enfants Malades, Paris, France), assessed data... Read More
01 March 2018
medwireNews: Cyproheptadine hydrochloride may have beneficial effects on growth that are unrelated to its influence on appetite in children with growth hormone (GH) insensitivity syndrome, report researchers. Maryam Razzaghy-Azar (Iran University of Medical Sciences, Tehran) and co-workers tested the medication in 15 such patients, following... Read More
01 February 2018
medwireNews: A study reports the characteristics of a series of patients with heterozygous mutations in the gene encoding aggrecan (ACAN). Fourteen of the 16 reported cases had short stature, with a median height standard deviation score (SDS) of –2.9, and mild skeletal dysplasia, and the other two cases had spondyloepiphyseal... Read More