Growth Disorders

30 September 2018
medwireNews: Two reports from the GeNeSIS observational study reveal the latest growth data and confirm that the safety profile of recombinant human growth hormone (rhGH) “remains favourable”. However, Christopher Child (Eli Lilly and Company, Windlesham, UK) and study co-authors note in The Journal of Clinical Endocrinology &... Read More
31 August 2018
medwireNews: The SYNERGY trial investigators report significant improvements in height velocity in South Korean children with idiopathic short stature (ISS) treated with daily recombinant human growth hormone (rhGH). During the first 6 months of treatment, the average height velocity increased from 5.63 cm/year to 10.08 cm/year in 59 children... Read More
31 July 2018
medwireNews: Real-time data on treatment adherence show its importance for good growth outcomes in patients taking recombinant human growth hormone (GH). Ekaterina Koledova (Merck Serono SA, Darmstadt, Germany) and colleagues made use of data from 1190 patients in the easypod™ connect observational study (ECOS), a register of patients using... Read More
01 June 2018
medwireNews: Growth hormone (GH) therapy has a greater impact on the metabolic outcomes of girls than boys, research suggests. This may indicate that girls with GH deficiency (GHD) should be more closely monitored during GH treatment, with the aim of modifying their lifestyles to counteract the metabolic changes, say Carla Giordano and co-... Read More
01 May 2018
medwireNews: Obese children with reduced peak stimulated growth hormone (GH) are likely to have hyperuricaemia, along with markers of increased cardiovascular risk, research shows. Peak GH in response to the arginine-levodopa stimulation test was markedly lower in the 78 obese children and adolescents in the study (average BMI standard... Read More
01 April 2018
medwireNews: Analysis of data from the NordiNet® International Outcome Study highlights continued delays in treating children with growth hormone deficiency (GHD) and the use of suboptimal doses in patients with Turner syndrome (TS). Researchers led by Michel Polak (Hôpital Universitaire Necker Enfants Malades, Paris, France), assessed data... Read More