Growth Disorders

02 January 2018
medwireNews: Factors including injection exhaustion create barriers to adherence in patients taking growth hormone (GH), but differ between children and adolescents, study findings suggest. When adherence was assessed with the 8-item Morisky Medication Adherence Scale (MMAS), Mania Radfar (Tehran University of Medical Sciences, Iran) and co-... Read More
30 November 2017
medwireNews: Heterozygous mutations in the Indian hedgehog gene (IHH) are a potential cause of idiopathic short stature (ISS), say researchers who report that children with these mutations appear to respond well to treatment with recombinant human growth hormone (rhGH). The researchers say their work has “extended the known phenotype... Read More
30 October 2017
medwireNews: Factors including age at initiation of growth hormone (GH) therapy and severity of inflammation during treatment determine whether children with juvenile idiopathic arthritis (JIA) will achieve a favourable growth outcome, study results show. The researchers stress that “clinical monitoring of growth remains crucial”, because the... Read More
29 September 2017
medwireNews: A study confirms the presence of impaired cardiac performance, body composition and cardiopulmonary function in children with growth hormone deficiency (GHD), all of which are reversed by GH replacement. Mariacarolina Salerno (Federico II University, Naples, Italy) and colleagues studied 17 boys and four girls with untreated GHD,... Read More
31 August 2017
medwireNews: Findings from the real-world NordiNet® International Outcome Study demonstrate clear benefits of early diagnosis and treatment initiation in patients with isolated growth hormone deficiency (GHD). However, Michel Polak (Hôpital Universitaire Necker Enfants Malades, Paris, France) and study co-authors stress that all patients... Read More
28 July 2017
medwireNews: Data from a dose-escalation study of the long-acting growth hormone (GH) somapacitan support its further development as a weekly treatment in children with GH deficiency (GHD), say researchers. The medication, which is currently being tested in a phase III trial in adults and a phase II trial in children, reversibly binds to... Read More