Plasma concentrations of the adrenal-derived 11-oxygenated-C19 androgen 11-ketotestosterone strongly correlate with salivary levels in children with congenital adrenal hyperplasia, UK researchers report.
A once-daily regimen of the thyroid hormone analogue Triac normalised serum levels of tri-iodothyronine in a phase II trial of paediatric and adult patients with transporter monocarboxylate transporter 8 deficiency.
The prevalence of overweight and obesity remains high among European children, say researchers, with “worrisome” rising trends in some countries, despite stabilising rates and downwards trends in other countries.
A Swedish study suggests that, as with girls, puberty has shifted to begin at an earlier age in boys.
Prepubertal children with type 1 diabetes have greater variability in their blood glucose levels than older children, research suggests.
In this podcast, Dr Shylaja Srinivasan discusses the care of children and adolescents with type 2 diabetes, and how the findings of the TODAY2 and Ellipse trials will inform treatment decisions.
The latest TODAY2 findings show rapid accumulation of cardiovascular risk factors and diabetes complications following a diagnosis of type 2 diabetes during childhood or adolescence.
The risk of a false–positive result on a low-dose adrenocorticotropic hormone stimulation test can be reduced in children by measuring cortisol levels at three consecutive time points instead of just one, researchers say.
Researchers have defined urinary steroid metabolite levels that indicate inadequate and excessive adrenal suppression for children with congenital adrenal hyperplasia undergoing glucocorticoid treatment.
Individuals with Noonan syndrome harbouring pathogenic variations in the PTPN11 gene respond well to treatment with recombinant human growth hormone, retrospective study data show.