Impaired glucose tolerance in obese youths frequently reverts to normal, although the chances of this happening are strongly influenced by ethnicity, researchers report in The Lancet Child & Adolescent Health.
The Endocrine Society has released a guideline for the diagnosis and treatment of hypothalamic–pituitary and growth disorders in survivors of childhood cancer.
The Restoring Insulin Secretion Pediatric Medication Study investigators have found that increased insulin resistance and hyperresponsive beta cells may explain the rapid progression of type 2 diabetes in children.
Receiving a Turner syndrome diagnosis after the age of 12 years increases the risk of patients later developing depression and substance use problems, and may also affect their competence, research suggests.
Repurposed insulin pump for PTH infusion an option for treatment-resistant paediatric hypoparathyroidism
Using an insulin pump to provide subcutaneous parathyroid hormone is an option for children with hypoparathyroidism and intestinal malabsorption, report researchers.
Cyproheptadine hydrochloride may have beneficial effects on growth that are unrelated to its influence on appetite in children with growth hormone insensitivity syndrome, report researchers.
Treating patients with congenital hypothyroidism with a high dose of levothyroxine from infancy does not compromise their IQ in young adulthood, report researchers.
A study reports the characteristics of a series of patients with heterozygous mutations in the gene encoding aggrecan.
The risk of having a repeat episode of severe hypoglycaemia is elevated for at least 4 years after a previous episode in children with type 1 diabetes, although the risk is highest during the first year, researchers report.
Heterozygous mutations in the Indian hedgehog gene are a potential cause of idiopathic short stature, say researchers who report that children with these mutations appear to respond well to treatment with recombinant human growth hormone.