The latest TODAY2 findings show rapid accumulation of cardiovascular risk factors and diabetes complications following a diagnosis of type 2 diabetes during childhood or adolescence.
The risk of a false–positive result on a low-dose adrenocorticotropic hormone stimulation test can be reduced in children by measuring cortisol levels at three consecutive time points instead of just one, researchers say.
Researchers have defined urinary steroid metabolite levels that indicate inadequate and excessive adrenal suppression for children with congenital adrenal hyperplasia undergoing glucocorticoid treatment.
Individuals with Noonan syndrome harbouring pathogenic variations in the PTPN11 gene respond well to treatment with recombinant human growth hormone, retrospective study data show.
Higher chance of diabetes remission but more reoperations for adolescents 5 years after bariatric surgery
The 5-year outcomes of the Teen-LABS cohort show that adolescents who undergo bariatric surgery have a good chance of achieving diabetes remission, but may require more reoperations than adult patients.
The randomised Ellipse trial has demonstrated significant blood glucose reductions with the glucagon-like peptide-1 receptor agonist liraglutide in children and adolescents with type 2 diabetes already taking metformin.
Health-related quality of life in women with Turner syndrome bears little or no relation to their height and whether they received growth hormone treatment as a child, say researchers.
Data from clinical practice support the option of adding gonadotrophin-releasing hormone analogue to growth hormone therapy in some clinical situations to extend the treatment window and optimise final height in children with idiopathic short stature.
Delayed puberty is common in the developed world, affecting over 2% of adolescents, and is associated with adverse health outcomes including short stature, reduced bone mineral density and compromised psychosocial health.
medwireNews goes behind the headlines, talking to researchers and independent experts about how the latest findings will impact clinicians caring for children with endocrine disorders.