Established genetic risk factors for adult-onset Graves’ disease apply equally in patients with a diagnosis in childhood, say researchers.
Adherence to recombinant human growth hormone has a strong influence on the growth response of children with growth hormone deficiency, especially during the second year of treatment, report researchers.
The Endocrine Society has released updated guidelines for the management of congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency.
Children who start to gain weight in their preschool years are at the highest risk of being obese in adolescence, shows a study in The New England Journal of Medicine.
Researchers have identified a novel mutation in the insulin-like growth factor 2 gene that they believe to be responsible for impaired pre- and postnatal growth in one of their patients.
Boys who have normal or minor abnormalities of their external genitalia despite a 45,X/46,XY karyotype have complications including reduced fertility, report researchers.
Two reports from the GeNeSIS observational study reveal the latest growth data and confirm that the safety profile of recombinant human growth hormone “remains favourable”.
Skewed inactivation of the X chromosome may underlie a proportion of cases of autoimmune thyroid disease in girls, research suggests.
Impaired glucose tolerance in obese youths frequently reverts to normal, although the chances of this happening are strongly influenced by ethnicity, researchers report in The Lancet Child & Adolescent Health.